To prevent infections, our multidisciplinary team monitors where diseases are spreading, and investigate to understand how and why. Our work covers a range of topics, all aiming to promote and implement better healthcare in Bangladesh and worldwide.
Our disease detectives are hard at work every day to understand microorganisms which cause deadly diseases.
Bill and Melinda Gates Foundation
Senjuti Saha
The project aims to explore and understand the individualized and heterogeneous immune responses to vaccines by employing advanced techniques in single-cell sequencing.
Read MoreBill & Melinda Gates Foundation
Yogesh Hooda
The project's purpose is to use AI-based tools to teach low- and middle-income scientists to perform modeling and prediction studies in public health, which are dominated by researchers...
Read MoreUniversity of Edinburgh, UK
Senjuti Saha
CHRF was a part of the RESPIRE project at the University of Edinburgh. The purpose of the project was to build research capacity in LMICs and ensure research is driven by the needs.
Read MoreSabin Vaccine Institute, USA
Samir Saha (Co-PI), Senjuti Saha (Co-PI)
This is a data management project on Multi-site Surveillance for Enteric-Fever in Bangladesh, Nepal, and Pakistan. It will support in managing the data generated by the SEAP projects in...
Read MoreSabin Vaccine Institute, USA
Samir Saha (Co-PI), Senjuti Saha (Co-PI)
This prospective study will generate comprehensive data on burden of typhoid and para-‐typhoid fever in Bangladesh, using the established network of sentinel and population-based sites....
Read MoreBill and Melinda Gates Foundation
Samir Saha (Co-PI), Senjuti Saha (Co-PI)
Using bacteriophages to study the spread of drug-resistant Salmonella Typhi across regions of Bangladesh
Read MoreStanford University
Samir Saha (Co-PI), Senjuti Saha (Co-PI)
A Mobile Autism Risk Initiative (AMARI) to Detect Autism Spectrum Disorder in Bangladesh Children under the Age of 4
Read MoreIllumina Corporate Foundation, USA
Senjuti Saha (PI)
Developing skills in Next Generation Sequencing techniques for young students, professionals, and scientists in Bangladesh
Read MoreGenome Research Limited (Sanger), UK
Samir Saha (Co-PI), Senjuti Saha (Co-PI)
In this project, we will be mainly using tools from Genotyping-by-sequencing to perform genomic surveillance of different infectious diseases existing in low and middle-income countries...
Read MoreBoston Children’s Hospital, USA
Samir Saha (Co-PI), Senjuti Saha (Co-PI)
A Global Pediatric Cell Atlas of Nasal and Oral Mucosa
Read MoreGenome Research Limited (Sanger), UK
Samir Saha (Co-PI), Senjuti Saha (Co-PI)
Global Pneumococcal Sequence Surveillance 2.0
Read MoreFoundation for Innovative New Diagnostics, Switzerland
Senjuti Saha (PI)
Building Capacity for Genomic Surveillance of SARS-CoV-2 and other pathogens in resource-constrained settings
Read MoreInternational Vaccine Institute (IVI), South Korea
Samir Saha (Co-PI), Senjuti Saha (Co-PI),
RSV infections in Bangladesh (RIB)
Read MoreStanford University
Senjuti Saha
The project focused on determining gestational age and preterm birth rates using metabolic profiles of neonates, particularly in low-resource settings.
Read MoreSt George’s, University of London (SGUL)
Samir Saha (Co-PI), Senjuti Saha (Co-PI)
This is a pilot study to work out the best way to apply an antiseptic called chlorhexidine to the skin of low birth-weight newborn babies who are admitted to the Dhaka Shishu hospital.
Read MoreBill and Melinda Gates Foundation
Samir Saha (Co-PI), Senjuti Saha (Co-PI)
In this project, we used techniques and tools from metagenomics to identify the microbes that affect the survival of typhi.
Read MoreUniversity of Edinburgh, UK
Samir Saha (Co-PI)
NIHR Global Health Research Unit on Respiratory Health
Read MoreJohns Hopkins University (USAID)
Abdullah Baqui (PI), Samir Saha (Co-PI)
Three simplified antibiotic regimes were tested for the treatment of neonatal sepsis, without danger signs. The regimes were compared with the standard group, 14 injections of penicillin...
Read MoreJohns Hopkins University (NIH)
Anne CC Lee (PI), Samir Saha (Co-PI)
Aimed to elucidate the etiology of genitourinary infections in women of rural Bangladesh.
Read MoreFondation Mérieux, France
Samir Saha (PI, Bangladesh)
This project aimed to validate a Real-‐Time PCR assay for the detection of S. Typhi, S. paratyphi A and S. spp, developed by Fondation Mérieux, in collaboration with Institut Pasteur, C...
Read MoreUniversity of Washington
Samir Saha (PI, Bangladesh)
The study has been designed to analyze the microbiome of respiratory specimens collected from <2 population and understand the impact of PCV introduction. Multi country project, overall...
Read MoreInstitute for Health Metrics and Evaluation (GAVI)
Samir Saha (PI)
This study was done in the rural population of Mirzapur in Bangladesh. The impact of PCV was measured in different age groups to understand the direct and indirect effects.
Read MoreBill & Melinda Gates Foundation
Samir Saha (PI, Bangladesh), Shabir Madhi (Overall PI)
Group B Streptococcus colonization in mother-newborn dyads and association with anti-capsular serotype-specific antibodies in low and middle-income countries in South Asia and Africa....
Read MoreCardiff University
Samir Saha (PI, Bangladesh), Timothy Walsh (Overall PI)
Aimed to collect paired organisms from the blood of babies with sepsis and rectal swabs of mothers. These paired strains were analyzed for non-susceptibility to antibiotics. These isolat...
Read MoreBill & Melinda Gates Foundation (BMGF Grant)
Samir Saha (PI)
This study aimed to find etiology of neonatal infections at 6 population-‐based sites in Bangladesh, India and Pakistan (Total Population 2,000,000; Eligible women 400,000 and 68,000 ne...
Read MoreSave the Children (WHO)
Nawshad Uddin Ahmed (PI), Samir Saha (Co-PI)
This study aimed to rigorously assess the benefits of an enhanced approach to community case management for pneumonia. This contributed to the evidence base for the revision of the WHO/U...
Read MoreSt George’s, University of London
Samir Saha (Co-PI)
Aimed to see the impact of PCV-10 vaccine on IPD (In-patient Department) cases in a rural population-based site in Sylhet
Read MoreSanofi Pasteur
Samir Saha (LPI)
The study generated comprehensive carriage data among newborns and children through longitudinal cohort analysis.
Read MoreBill & Melinda Gates Foundation
Samir Saha (PI)
To see the impact of PCV-10 on meningitis, pneumonia, and sepsis by using “before-after” and case-‐control studies using “indirect cohort”. This study will be done in a network of 4 s...
Read MoreBill & Melinda Gates Foundation
Samir Saha (PI, Bangladesh)
This project was to support Microbiology & Quality assurance (QA) of Nasopharyngeal Carriage studies in India at the KEM Hospital in Pune and King George's Medical University in Lucknow.
Read MoreGlaxoSmithKline (GSK plc)
Samir Saha (PI)
The purpose of the project was to see the impact of PCV-10 on meningitis, pneumonia, and sepsis by using “before-after” and case-control studies using an “indirect cohort”. This study...
Read MorePfizer
Samir Saha (PI)
The study enrolled otitis media cases to elucidate the effectiveness and impact of PCV-10 using the before (pre-vaccine) and after (post-vaccine) design. This outpatient-based project...
Read MoreBill & Melinda Gates Foundation
Samir Saha (PI)
This study worked to explore the aetiology among the cerebrospinal fluids where no aetiology could not be detected using the available technologies like culture, serology, PCR, or rtPCR.
Read MoreBill and Melinda Gates Foundation
Samir Saha (PI)
This study examined the burden of rotaviral diarrhea in hospitalized children of ≤5 years of age, as well as the incidence of rotaviral diarrhea in urban Bangladesh. It helped to improve...
Read MoreBill and Melinda Gates Foundation
Senjuti Saha (PI), Samir Saha (Co-PI)
To set up a mid-throughout sequencing facility (NextSeq2000) in Bangladesh for whole genome sequencing of bacterial and viral pathogens, and metagenomic sequencing of biological samples.
Read MoreBill and Melinda Gates Foundation
Samir Saha (PI)
To enhance COVID diagnostic in Bangladesh for pediatric and adult population, generate strong epidemiological data, determine rates of infections in health care providers, establish a ge...
Read MoreBill & Melinda Gates Foundation
Samir Saha (PI)
This project generated evidence about both the direct and indirect effects of high-burden diseases like RSV infections and guided informed policy decisions based on the impact of disease...
Read MoreEdinburgh University (NIHR Fund)
Samir Saha (PI, Bangladesh)
To reduce the impact of and the number of deaths caused by respiratory diseases in South Asia (RESPIRE) Multi country project, overall PI: Prof. Aziz Sheikh (PI)
Read MoreInternational Vaccine Institute (IVI)
Samir Saha (PI)
Real-time Tracking of Neglected Bacterial Diseases and Resistance Patterns in Asia (TunDRA)
Read MoreThe Hospital for Sick Children, Canada
Senjuti Saha (PI), Samir Saha (Co-PI)
CHRF was the key partner in laboratory-related activities that pertained to the SEPSIS Study's primary endpoint. Specifically, CHRF was engaged in blood specimen collection, laboratory a...
Read MoreGeorge Mason University, USA
Samir Saha (Co-PI)
Through this project, we studied the emergence of Campylobacter bacteria in rural regions of Bangladesh and how they are transmitted.
Read MoreImmuneMed Inc (Right Fund)
Samir Saha (Co-PI)
Develop Immunochromatographic based rapid diagnostic test for the both Typhoid fever and Paratyphoid fever
Read MoreSt George’s, University of London
Samir Saha (Co-PI)
Efficacy and safety of chlorhexidine cleansing in reducing bacterial skin colonization of hospitalized low birthweight neonates: A pilot trial (NeoCHG)
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